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What Is the Significance of the Nonce in the PoW Process?

The nonce (Number Only Used Once) is the variable that miners iterate on to change the block header's hash. It is the key input they manipulate in their search for a hash that meets the target difficulty.

Since the rest of the block data is fixed, the nonce is the only part that can be rapidly changed. Finding the correct nonce is essentially the act of mining a block.

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